Endocrine Abstracts

Merkel cell cancer, is a very rare, malignant, neuroendocrine tumour. of the skin The cause is not known. Is and often aggressive malignancy with high tendency for local recurrence, lymph node involvement and distant metastasis and a poor prognosis and rapid progression. The Merkel cell is located in or near the basal layer of the epidermis and is closely associated with terminal axons. The aims in this study we report four cases of Merkel cell tumor of the skin(1 primary and ...

Neuroblastoma is a tumor that originates from immature nerve cells. It is the most common extracranial solid tumor in children, but is extremely rare in adults.Aim: The role of MIBG scintigraphy in diagnosis and follow-up of patient with neuroblastoma.Case report: A 55-year-old woman underwent for regular abdomen ultrasound examination. Sonography revealed inhomogeneous, predominantly isoehogenic tumor mass above the upper lobe of ...

Introduction: Many studies have shown that dietary protein content may play a role in weight management. Moreover, it has been found that diets high in protein (either animal or plant) significantly reduced markers of insulin resistance and hepatic necroinflammation independently of body weight change. This study aimed to examine the effect of dietary protein source on body composition and cardiometabolic risk factors in young adults with obesity during anti-inflammatory weigh...

Introduction: Surgical management of clinically N0 (cN0) patients with thyroid carcinomas remains debatable due to various reported frequencies of lymph node (LN) metastases. The aim of this paper was to present usefulness of sentinel lymph node biopsy (SLNB) of jugulo-carotid regions after methylene blue dye (MBD) mapping in intraoperative selection of cN0 patients with papillary and medullary thyroid carcinomas for one-time lateral neck dissection (LND).<p class="abstext...

Introduction: The isolated hyperparathyroidism (IHP) is a metabolism disorder characterized by an absent or low parathormon (PTH) and hypocalcemia. It can be acquired, autoimmune, a result of some syndrome and as a part of a family (FIHP). FIHP is an extremely rear disease which is inherited auto somatic dominant or auto somatic recessive as a result of a mutation of one or several different genes. Pathological calcifications in the cerebrum are a secondary form of calcificati...

A 26-year-old woman was referred to our outpatient clinic, presenting with growing left sided neck mass. She was in remission of Graves’ disease for the last two years.Ultrasound examination revealed isoechogenic nodule with microcalcifications in the upper third of the left thyroid lobe measuring 9×6×6 mm and conglomerate of lymph nodes on the left side of the neck, the largest node measuring 37×21×13 mm. Behind the lower pole of the left thyroid lobe...

Introduction: Serum calcitonin level (sCT) is a precise marker for medullary thyroid carcinoma (MTC). However, lymph node (LN) metastases can be found in lower sCT, as well, and preoperative ultrasound may provide false negative findings on regional LNs. The aim was to present original technique of sentinel lymph node (SLN) biopsy of jugulo-carotid regions, after methylene blue dye mapping procedure, and its usefulness for selection of clinically N0 patients with MTC for modif...

Introduction: Overt hypothyroidism and severe subclinical hypothyroidism (ScH) are associated with dyslipidaemia, and its condition is reversible after thyroid replacement therapy. We investigated the effect of levothyroxine therapy on lipid parameters in patients with mild form of subclinical hypothyroidism (ScH).Material and methods: Fifty-seven patients with newly diagnosed ScH with TSH levels below 10 mU/l and 30 age and sex-matched healthy subjects ...

Introduction: Serum calcitonin levels (sCT) in medullary thyroid carcinoma (MTC) correlate with the tumour size and disease progression. Lymph node (LN) metastases can be verified even in sCT lower than 100 pg/ml. The extent of LN dissection has not yet been standardised. The aim of this pilot study was to show our experience with sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in selection of patients with MTC for modified radical neck dissection (MRND).<p ...

Background: Well-differentiated thyroid carcinoma in children is rare but it shows aggressive behaviour. Gross lymph node metastases and distant metastases are common on first clinical presentation.Patients and methods: During 33 years (1981–2014) at the Institute of Oncology and Radiology of Serbia 24 children were operated due to papillary thyroid carcinoma. Mean age was 12.6 (range 7–16) years. At the time of diagnosis 12.5% patients had lun...